Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease - Ruđer Bošković Institute

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The goal of this project is to elucidate the molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease (NPC). We will investigate the role of protease BACE1, the key Alzheimer's disease (AD) enzyme, in the pathogenesis of NPC disease. We hope that our findings will elucidate BACE1 as a novel target for treating/ameliorating NPC disease.
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
Silva Katusic Hecimovic - Senior Scientist - Ruđer Bošković
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
PDF) Pharmacological Activation of LXRs Decreases Amyloid-β Levels
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
Silva Katusic Hecimovic - Senior Scientist - Ruđer Bošković
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
PDF) Overlapping Neuroimmune Mechanisms and Therapeutic Targets in
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
Niemann–Pick type C disease: cellular pathology and
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
PDF] Efficient Investigation and Differential Diagnosis of
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
Converging pathways in neurodegeneration, from genetics to
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
Niemann–Pick type C disease: cellular pathology and
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
A proposed model for the pathogenesis of Niemann-Pick disease type
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
IJMS, Free Full-Text
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
Our research - Ruđer Bošković Institute
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
Lysosomal dysfunction as a common mechanism of neurodegenerative
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
PDF) Overlapping Neuroimmune Mechanisms and Therapeutic Targets in
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
PDF) Impaired Retromer Function in Niemann-Pick Type C Disease Is
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease  - Ruđer Bošković Institute
Involvement of the Choroid Plexus in the Pathogenesis of Niemann
de por adulto (o preço varia de acordo com o tamanho do grupo)