JDB, Free Full-Text

Por um escritor misterioso

Descrição

The extracellular matrix (ECM) guides and constrains the shape of the nervous system. In C. elegans, DIG-1 is a giant ECM component that is required for fasciculation of sensory dendrites during development and for maintenance of axon positions throughout life. We identified four novel alleles of dig-1 in three independent screens for mutants affecting disparate aspects of neuronal and glial morphogenesis. First, we find that disruption of DIG-1 causes fragmentation of the amphid sheath glial cell in larvae and young adults. Second, it causes severing of the BAG sensory dendrite from its terminus at the nose tip, apparently due to breakage of the dendrite as animals reach adulthood. Third, it causes embryonic defects in dendrite fasciculation in inner labial (IL2) sensory neurons, as previously reported, as well as rare defects in IL2 dendrite extension that are enhanced by loss of the apical ECM component DYF-7, suggesting that apical and basolateral ECM contribute separately to dendrite extension. Our results highlight novel roles for DIG-1 in maintaining the cellular integrity of neurons and glia, possibly by creating a barrier between structures in the nervous system.
JDB, Free Full-Text
Intravenous edaravone treatment in ALS and survival: An exploratory, retrospective, administrative claims analysis - eClinicalMedicine
JDB, Free Full-Text
JBD Smart BMS 6S~21S 100A 200A For LiFePO4& Li-ion Battery With Balance NTC for Freeshipping – Jiabaida BMS
JDB, Free Full-Text
JDB - Quick Guide
JDB, Free Full-Text
JDB Yes on the App Store
JDB, Free Full-Text
De Bow's Review - Wikipedia
JDB, Free Full-Text
SnowWolf Ease Disposable Vape - 8000 Puffs
JDB, Free Full-Text
JBD/Xiaoxiang BMS Apps List
JDB, Free Full-Text
6 Java debugging tools you should know · Raygun Blog
JDB, Free Full-Text
JDB Slots Play JDB Demo Slots
JDB, Free Full-Text
BasketBall Clinics – Fallbrook Community Center Friends
de por adulto (o preço varia de acordo com o tamanho do grupo)