Bioengineering, Free Full-Text
Por um escritor misterioso
Descrição
Perceptual and statistical evidence has highlighted voice characteristics of individuals affected by genetic syndromes that differ from those of normophonic subjects. In this paper, we propose a procedure for systematically collecting such pathological voices and developing AI-based automated tools to support differential diagnosis. Guidelines on the most appropriate recording devices, vocal tasks, and acoustical parameters are provided to simplify, speed up, and make the whole procedure homogeneous and reproducible. The proposed procedure was applied to a group of 56 subjects affected by Costello syndrome (CS), Down syndrome (DS), Noonan syndrome (NS), and Smith–Magenis syndrome (SMS). The entire database was divided into three groups: pediatric subjects (PS; individuals < 12 years of age), female adults (FA), and male adults (MA). In line with the literature results, the Kruskal–Wallis test and post hoc analysis with Dunn–Bonferroni test revealed several significant differences in the acoustical features not only between healthy subjects and patients but also between syndromes within the PS, FA, and MA groups. Machine learning provided a k-nearest-neighbor classifier with 86% accuracy for the PS group, a support vector machine (SVM) model with 77% accuracy for the FA group, and an SVM model with 84% accuracy for the MA group. These preliminary results suggest that the proposed method based on acoustical analysis and AI could be useful for an effective, non-invasive automatic characterization of genetic syndromes. In addition, clinicians could benefit in the case of genetic syndromes that are extremely rare or present multiple variants and facial phenotypes.
asaiojournal on X: Read the April 2023 Issue! #OrganPreservation #CardiogenicShock #ECMO #LVAD #Bioengineering #biocompatibility #pedsVAD #pedsECMO #pedsICU #bivalirudin v #heparin #Iron #Impella #Infection #ArtificialOrgans
Finding Free Full-text PubMed Central Articles in PubMed
PDF) ACID: a free tool for drug repurposing using consensus inverse docking strategy
Biomedical Engineering in Scandinavia
Annual Review of Biomedical Engineering
Bioengineering An Open Access Journal from MDPI
Bioengineering icon simple element Royalty Free Vector Image
Vastu Ppt Get File - Colaboratory
Bioengineering word concepts banner. Biotechnology. Molecular biology, biomedical engineering. Presentation, website. Isolated lettering typography idea with linear icons. Vector outline illustration Stock Vector
Bioengineering, Free Full-Text
Biomedical Engineering MEng, Study
Biomedical Engineering Society (@bmesociety) • Instagram photos and videos
Biomedical Engineer Cover Letter Example (Free Guide)
Current Directions in Biomedical Engineering
4,492 Bioengineering Royalty-Free Images, Stock Photos & Pictures
de
por adulto (o preço varia de acordo com o tamanho do grupo)
